Comprehensive orthodontic treatment of impacted teeth / 口腔疾病防治

@#Impacted teeth are a kind of complex malocclusion, and their incidence differs among different races, sexes and dental positions. The causes of impacted teeth include systemic factors and local factors, such as endocrine disorders, malnutrition, and acute and chronic infectious diseases. Local factors can cause abnormal tooth development or eruption during the process from tooth development to tooth eruption, such as damaged permanent tooth embryos caused by local inflammation or trauma, insufficient eruption space caused by premature loss of deciduous teeth, and eruption disorders caused by local lesions for example hyperplasia or odontoma. The clinical manifestation of impacted teeth is the absence of a permanent tooth in a normal position. We can use cone beam CT (CBCT) to locate the impacted teeth. Comprehensive orthodontic treatment includes surgical-assisted eruption, extraction of retained deciduous teeth or supernumerary teeth, removal of lesions such as odontomas and cysts, and expansion of the orthodontic space. When the dysfunctional local soft and hard tissues are removed during a surgical operation, the tooth still cannot sprout smoothly, and it needs to be assisted by orthodontic traction-guided eruption or extracted and autotransplantation. A clear diagnosis, evaluation of the difficulty of treatment and appropriate treatment are the keys to improving the success rate of treatment. In this paper, the epidemiology, etiology, diagnosis and corresponding treatment methods of impacted teeth will be reviewed, and the orthodontic treatment of impacted teeth will be comprehensively described to provide a reference for clinicians about the treatment of impacted teeth.

Research progress of total pancreatectomy with islet autotransplantation for chronic pancrea-titis or recurrent acute pancreatitis / 中华消化外科杂志

Total pancreatectomy with islet autotransplantation, (TPIAT) is a complex surgical procedure for recurrent acute pancreatitis (RAP) and chronic pancreatitis, which can eliminate the risk of pancreatitis for pancreatic cancer and reduce the threat of severe diabetes mellitus. An increa-sing number of centers, here in the United States and internationally, are performing TPIAT and studies emerging from multiple centers highlight the benefits and persistent challenges of TPIAT for RAP and chronic pancreatitis. However, clear guidance on indications, contraindications, evaluation, timing of treatment and follow-up is lacking. The author reviews the history of TPIAT, and discusses the current state of TPIAT including indications of treatment, preoperative evaluations, surgical method, islet isolation and portal vein infusion, and postoperative management and a single center′s experience in TPIAT. A multiple center study with large numbers of patients will be critical to optimizing the successful application of this procedure.

Knowledge, Attitude, and Practice of Autotransplantation Among the Practicing Pediatric Dentists in Chennai – A Questionnaire Study

Background: Autotransplantation is a minor surgical procedure which involves transplantation of teeth within the same oral cavity. For children, autotransplantation may be considered as a provisional measure with good survival probability. It offers a viable biological approach for replacing the missing teeth and also for orthodontic treatments in children. Aim: The aim of this study is to assess the knowledge, attitude, and practice of autotransplantation among pediatric dentists in Chennai, India. Methods: An 18?item questionnaire was developed, piloted, and distributed among 100 practicing pediatric dentists in Chennai, India. Descriptive statistical analysis was done using Chi?square test. Results: Seventy valid responses from the practicing pediatric dentists were obtained. Among them, 39.7% had an experience of 5–10 years, 47.1% practiced less than 5 years, and 13.2% had experience more than 10 years. Analysis of the responses showed that 76.5% of the pediatric dentists were aware of the procedure but have not observed autotransplantation being done. Among the respondents, 95.6% have not performed this technique and 40.6% of them were not sure of the prognosis. Atraumatic extraction of donor tooth was considered to be a major limitation in autotransplantation by 41.8% of the pediatric dentists. From the responses received, 95.6% were interested in gaining more information with majority opting for more hands on workshops on the technique of autotransplantation. Conclusion: Though most of the respondents were aware of autotransplantation procedure, they have not practiced it due to inadequate training

Clinical efficacy and safety of ex-vivo liver resection and liver auto-transplantation: a bayesian single-arm Meta-analysis / 中华肝胆外科杂志

Objective:To evaluate the clinical efficacy and safety of ex vivo liver resection and autotransplantation (ELRA) by using a Bayesian single-arm Meta-analysis.Methods:Databases of PubMed, Embase, Cochrane Library, Web of Science, CNKI, and Wanfang were searched from January 1, 1990 to December 30, 2021 on ELRA studies. The Bayesian one-arm Meta-analysis was performed by using the statistical software of R (V4.1.2) and the Markov chain-Monte Carlo method was used to simulate the posterior distribution. The mortality rate within 30 days after operation, 1-year survival rate, major postoperative complications, R 0 resection rate and other related indexes were analyzed. Results:A total of 20 studies with 436 patients were included. Bayesian single-arm Meta-analysis showed that the 1-year survival rate after ELRA was 83.24% [95% highest posterior density ( HPD): 72.40%-92.05%]. The 1-year survival rates after surgery were 88.66% (95% HPD: 81.52%-94.50%) for patients with hepatic alveolar echinococcosis and 61.29% (95% HPD: 38.53%-93.68%) for patients with hepatic malignancies, respectively. The mortality rate within 30 d after surgery, the incidence of significant postoperative complications, and the R 0 resection rate were 6.96% (95% HPD: 4.47%-10.15%), 27.91% (95% HPD: 19.00%-38.30%), and 99.84% (95% HPD: 37.61%-100.00%), respectively. Renal failure was the most frequent cause of death after ELRA. Conclusion:ELRA is indicated for hepatic malignancies and hepatic alveolar echinococcosis when intrahepatic resection cannot be accomplished in vivo. The greatest benefit is observed in patients with hepatic alveolar echinococcosis, while only some patients with hepatic malignancies can benefit. The indications for ELRA for hepatic malignancies need to be further studied to define the subgroup of patients who can benefit from this operation.

Dental autotransplantation as a alternative treatment for the loss of permanent anterior teeth in children

ABSTRACT Introduction: Autotransplantation is defined as the surgical movement or transposition of a tooth from its original site to a recipient alveolus, in the same patient. It has high success rates when performed within predefined parameters. Objective: This study aims to describe the advantages of a dental autotransplantation protocol based on a multidisciplinary approach and using cone beam computed tomography, computer-aided planning, and rapid prototyping of the donor tooth, enabling the preparation of a surgical guide and postoperative protective plate. This article discusses the indications and contraindications for autotransplantation, as well as the selection criteria for the tooth to be transplanted and the transoperative care essential for its success. The parameters for post-operative control are described, in addition to the variables of success and failure to be considered. Conclusions: When analyzing the treatment options available for children with anterior tooth loss and the psychosocial impact on these patients, autotransplantation is considered not only an alternative treatment, but the only viable option for their functional, aesthetic, and social reestablishment.

RESUMO Introdução: O autotransplante é definido como a transposição cirúrgica de um dente do seu local original para um alvéolo receptor no mesmo indivíduo, e apresenta altas taxas de sucesso, quando realizado dentro de parâmetros predefinidos. Objetivo: O presente estudo tem como objetivo descrever as vantagens de um protocolo de autotransplante dentário baseado em uma abordagem multidisciplinar e utilizando tomografia de feixe cônico, planejamento assistido por computador e prototipagem rápida do dente doador - possibilitando a confecção de um guia cirúrgico e placa protetora pós-operatória. Nesse artigo, serão discutidas as indicações e contraindicações do autotransplante, assim como os critérios de seleção do dente a ser transplantado e os cuidados transoperatórios essenciais para o seu sucesso. Serão descritos os parâmetros para controle pós-transplante, assim como as variáveis de sucesso e insucesso a serem consideradas. Conclusão: Ao analisar as opções de tratamento disponíveis para crianças com perdas dentárias na região anterior e o impacto psicossocial nesses indivíduos, deve-se considerar que o autotransplante não se constitui somente em uma alternativa de tratamento, mas sim na única opção viável para o restabelecimento funcional, estético e social desses pacientes, reinserindo-os em seu meio.

Autotrasplante Digital: Reporte de Caso Clínico / Digital Autotransplantation: Clinical Case Report

El trasplante dentario autólogo se define como el po-sicionamiento de una pieza dentaria autóloga en un alvéolo post extracción o en un lecho formado qui-rúrgicamente. Actualmente, siguiendo los criterios de selección adecuados y una técnica quirúrgica mi-nuciosa, resulta una alternativa terapéutica ideal en ciertos pacientes. La gran variabilidad de implantes dentales y alternativas de injertos óseos han resuelto el problema de sustituir una pieza dentaria perdida. En los pacientes en crecimiento o con potencial de crecimiento residual del proceso alveolar, se pone en evidencia el inconveniente que puede representar la colocación de implantes, lo que hace necesario ree-valuar la conservación de dientes y la utilización de técnicas quirúrgicas clásicas. Las tasas de éxito de los autotrasplantes autólogos han aumentado con el tiempo, alcanzando cifras mayores al 90%. En el pre-sente artículo se reporta un caso clínico de autotras-plante dentario con planificación digital y una réplica tridimensional de la pieza a trasplantar (AU)

Autologous tooth transplantation is defined as the positioning of an autologous tooth in a post-extraction socket or in a surgically formed bed. Currently, following the appropriate selection criteria and a meticulous surgical technique, it is an ideal therapeutic alternative in certain patients. The great variability of dental implants and bone graft alternatives have solved the problem of replacing a lost tooth. In growing patients or with potential for residual growth of the alveolar process, the inconvenience that implant placement can represent is evident, which makes it necessary to reevaluate tooth conservation and the use of classic surgical techniques. The success rates of autologous autologous transplants have increased over time, reaching figures greater than 90%. This article reports a clinical case of dental autotransplantation with digital planning and a three-dimensional replica of the piece to be transplanted (AU)

Autotrasplante Dental Utilizando Simulación Virtual y un Prototipo de Modelo de Impresión 3D

RESUMEN: La técnica de autotrasplante dental se ideó como opción terapéutica ante la pérdida o ausencia de dientes por traumatismos, caries, agenesias, exfoliación temprana, iatrogenias, u otros factores. Consiste en extraer un diente desde su posición original para implantarlo en un solo acto quirúrgico en una zona edéntula, sea ésta un alveolo postextracción o alveolo confeccionado quirúrgicamente. Un resultado exitoso, requiere una meticulosa selección de candidatos, para esto, se debe considerar la ausencia de patologías y condiciones de orden local o sistémico que dificulten una adecuada cicatrización de heridas y reparación tisular. Nuevas herramientas para facilitar éxito clínico, como la planificación y simulación virtual, junto con la impresión de prototipos en tres dimensiones (3D), permitirían optimizar posibles osteotomías y una implantación del diente donante de manera fácil y en tiempos quirúrgicos mínimos, favoreciendo la disminución de la complejidad quirúrgica, además de la reparación y regeneración de tejidos pulpares y periodontales. El objetivo de este artículo es reunir una serie de consideraciones para optimizar la técnica de autotrasplante dental.

ABSTRACT: The dental autotransplantation technique was devised as a therapeutic option for the loss or absence of teeth due to trauma, caries, agenesis, early exfoliation, iatrogenesis, or other factors. It consists of extracting a tooth from its original position to implant it in a single surgical act in an edentulous area, be it a post-extraction socket or a surgically made socket. A successful result requires meticulous selection of candidates, for this, the absence of pathologies and local or systemic conditions that hinder adequate wound healing and tissue repair must be considered. New tools to facilitate clinical success,such as planning and virtual simulation, together with the printing of prototypes in three dimensions (3D), would allow possible osteotomies and an implantation of the donor tooth in an easy way and in minimal surgical times, favoring the decrease of surgical complexity, in addition to the repair and regeneration of pulp and periodontal tissues. The objective of this article is to gather a series of considerations to optimize the dental autotransplantation technique.

Rapidliver autotransplantation by magnetic anastomotic technique during ex situ liver resection in an animal model / 中华器官移植杂志

Objective:To invent a set of novel magnetic anastomotic device based upon the technique of magnetic compression anastomosis(MCA)for rapid venous reconstruction during ex situ liver resection, and verify its clinical value and performance in animal models. Methods:Fiften adult mongrel dogs of either gender underwent the ex situ liver resection. The novel magnetic vessel anastomosis device for the venous reconstruction of liver autotransplantation procedure was performed on 8 mongrel dogs(MCA group), and the traditional handsewing technique was used on 5 additional dogs(THS group). Time for completing venous reconstruction and time of venous anastomosis, venous velocity, intraoperative and postoperative survival and complications were recorded. Patency was detected via color Doppler ultrasound scans and X-ray cholangiography after surgery. The changes of intestinal lumen and kidney were also observed. Results:The time required to perform IVC and PV reconstruction for liver autotransplantation was significantly shorter for the magnetic vessel anastomosis device(9.5±2.5) min than for THS(30.7±3.4) min. There was significant difference in anhepatic period( P=0.0000). After operation, except one died, other nine animals in group A survived after operation but all five cases died in the THS group during liver autotransplantation. Vascular X-ray angiography and color Doppler ultrasound found blood flow MCA group normal, and there wasn't stoma stenosis. Conclusions:MCA technique could be fast and efficacious to complete venous reconstruction for liver autotransplantation in ex situ liver resection operation, and helpful to reduce organ ischemia-reperfusion injury.

Postoperative complications of ex vivo liver resection combined with autologous liver transplantation in treatment of advanced hepatic alveolar echinococcosis at high altitude and related prevention and treatment strategies / 临床肝胆病杂志

Objective To investigate the postoperative complications of ex vivo liver resection combined with autologous liver transplantation in the treatment of end-stage hepatic alveolar echinococcosis at high altitude and related prevention and treatment strategies. Methods Surgical data and follow-up data were collected from 11 patients with end-stage hepatic alveolar echinococcosis who underwent autologous liver transplantation in Qinghai People's Hospital from January 2013 to March 2019, and intraoperative and postoperative conditions were analyzed. Results All 11 patients underwent autologous liver transplantation successfully, without intraoperative death, among whom 2(18.18%) underwent hemi-extracorporeal hepatectomy and 9 (81.82%) underwent total extracorporeal hepatectomy. For the reconstruction of the retrohepatic inferior vena cava, 2 patients (18.18%) underwent reconstruction with the autologous great saphenous vein, 4 patients (36.36%) underwent reconstruction with artificial vessels, and the autologous retrohepatic inferior vena cava was preserved in 5 patients (45.45%). For biliary reconstruction, 8 patients (72.73%) underwent choledochoenterostomy and 3 (27.27%) underwent choledochocholedochostomy. The main postoperative complications of the 11 patients included bleeding in 2 patients (18.18%), bile leakage and abdominal infection in 4 patients (36.36%), bilioenteric anastomotic stenosis in 1 patient (9.09%), thrombus in 2 patients (18.18%), pulmonary infection and pleural effusion in 2 patients (18.18%), and echinococcosis recurrence in 1 patient (9.09%). Of all 11 patients, 2 (18.18%) died during the perioperative period, and the other 9 patients (81.82%) were improved and discharged. Conclusion Bleeding, biliary complications, and infection are the main causes of death in patients undergoing autologous liver transplantation at high altitude. An accurate understanding of surgical indication, careful multidisciplinary evaluation before surgery, superb operation during surgery, standardized surgical procedures, and fine perioperative management are the key to reducing perioperative mortality, avoiding and reducing postoperative complications, and achieving good long-term survival in patients undergoing autologous liver transplantation.

Ex-vivo repair for multiple and intraparenchymal renal artery aneurysms / Reparo Ex Vivo de Aneurismas Intraparenquimatosos Múltiplos da Artéria Renal

Abstract A 45-year-old woman with known hypothyroidism and no other comorbidities was incidentally found to have multiple right renal artery aneurysms. The largest aneurysm measured 5 x 4.5 cm and arose from an inferior segmental branch while two smaller aneurysms arose from an upper segmental branch of the right renal artery. We performed an ex-vivo repair with reverse saphenous vein graft under cold preservation followed by orthotopic kidney auto-transplantation. Her postoperative course was unremarkable and at 1-year follow-up her right kidney is preserved. In this article, we report successful treatment of complex multiple right renal artery aneurysms and describe the surgical technique used for successful repair.

Resumo Uma mulher de 45 anos com hipotireoidismo conhecido e sem outras comorbidades teve achado incidental de múltiplos aneurismas da artéria renal direita. O maior aneurisma media 5 x 4,5 cm e tinha origem no ramo segmentar inferior, juntamente com dois pequenos aneurismas originários do ramo segmentar superior da artéria renal direita. Realizamos o reparo ex vivo com enxerto reverso de veia safena, sob preservação a frio, seguido de autotransplante renal ortotópico. O pós-operatório ocorreu sem intercorrências, e a paciente teve o rim direito preservado no seguimento de 1 ano. Neste artigo, relatamos o tratamento bem-sucedido de múltiplos aneurismas complexos da artéria renal direita e descrevemos a técnica cirúrgica utilizada para o reparo bem-sucedido.

Efficacy of Lung Autotransplantation for Central Non-small Cell Lung Cancer / 中国肺癌杂志

BACKGROUND@#Pneumonectomy and sleeve resection are routine operations for the treatment of central non-small cell lung cancer (NSCLC), but some patients suffered of central NSCLC, whose pulmonary function is too poor to tolerate pneumonectomy, or the tumor involves the bronchus and pulmonary artery extensively,it is hard to perform bronchovascular sleeve lobectomy. The aim of this study is to assess the feasibility of lung autotransplantation in the treatment of central NSCLC.@*METHODS@#The clinical data of 3 cases with central NSCLC treated by lung autotransplantation was reviewed from December 2016 to December 2018. One patient underwent double sleeve resection of left upper lobe with end-to-end anastomosis of the bronchus. Because the resection of the pulmonary artery was too long to perfrom a tension-free anastomosis, the inferior pulmonary vein was cut off, then the left lower lobe was moved up for an anastomosis of the inferior pulmonary vein and the stump of the superior pulmonary vein. In the other 2 cases, left pneumonectomy was performed directly, and the upper left lobe was excised in vitro. The lower left lobe was reset to the chest after trimming and flushing and then the bronchus, pulmonary artery and pulmonary vein were anastomosed in turn.@*RESULTS@#The average operation time was 333 min, the average time of vascular occlusion was 86 min, the average blood loss was 450 mL, and the average hospital stay was 18.7 d; Perioperative complications included a case of bronchial obstruction, which improved after sputum aspiration through bronchofibroscope. The average follow-up period was 20 mon; One case died of cancer, one case had recurrence of anastomotic stoma and brain metastasis, one case had 4R lymph node metastasis (stable condition after chemotherapy), and one case survived without recurrence.@*CONCLUSIONS@#For patients with central NSCLC with extensive tumor invasion, thus inability to tolerate sleeve resection or pneumonectomy, autologous lung transplantation can preserve lung function to the greatest extent with a complete tumor resection and improve postoperative quality of life.

Transplante dentário autógeno: revisão de literatura e relato de caso clínico / Autogenous dental transplantation: literature review and clinical case report

Objetivo: o transplante dentário é uma técnica cirúrgica que consiste na movimentação cirúrgica de um dente, podendo ser vital ou tratado endodonticamente, o qual é submetido a uma avulsão do seu local de origem e implantado em outro alvéolo. Relato de caso: paciente do sexo masculino, 18 anos, normossistêmico, buscou atendimento no Serviço de Cirurgia e Traumatologia Bucomaxilofacial da Pontífica Universidade Católica do Rio Grande do Sul (PUCRS) apresentando cárie no dente 26. O plano de tratamento consistiu em realizar um autotransplante do dente 28 para o alvéolo do dente 26. Após 8 meses do transplante, o dente apresentava em boas condições periodontais avaliadas clinicamente e em exame radiográfico. Considerações finais: o transplante dentário autógeno pode ser uma opção viável para a substituição de molares ausentes ou com cáries extensas, como mostrado no presente caso clínico. (AU)

Objective: Dental transplantation is a surgical technique that consists of the surgical movement of an either vital or endodontically treated tooth, which is subjected to an avulsion from its place of origin and implanted in another socket. Case report: An 18-year-old male patient, normosystemic, attended the Oral and Maxillofacial Traumatology Surgery Service of PUCRS presenting a decayed tooth 26. The treatment plan consisted of the autotransplantation of tooth 28 to the alveolus of tooth 26. Eight months after the transplantation, the tooth presented satisfactory periodontal conditions by clinical and radiographic assessments. Final considerations: The autogenous dental transplantation may be a viable option for replacing absent molars or with extensive caries, as shown in the present clinical case. (AU)

Histological Changes of Spleen Autotransplanted in the Omentum of Rats

Introduction: The spleen is a lymphoid organ that plays an important role in the body's defense against organisms, participation in blood filtration process, phagocytosis and immunoglobulin production. When splenectomy due to severe splenic trauma or hematological disorder is inevitable, spleen autotransplantation may be the only option to preserve the spleen. It has not been determined the structural rearrangements after transplanting in comparison with the amount of transplanted spleen. The aim of this study was to evaluate the histological changes of spleen autotransplanted in the omentum of rats.Materials and Methods: In this experimental study, 16 male Wistar rats underwent splenectomy and transplanting three pieces of splenic tissue consists of 10-15% of the greater omentum. The rats were divided to two equal groups; Eightcaseswere randomly separated and followedfor 6 months (Group Au-6) and 8 other cases also were separated for 12months'follow-up (group Au-12). At the end of follow-up period, after the re-operation ofautotransplanted rats, the splenictissues underwent the macroscopic and microscopic examination and two groups were compared together.Results: After laparotomy, splenic tissues were detected in all cases (8/8, 100%) of Au-6 group and 7 cases (87.5%) of Au-12 group. It’s observed no significant difference between two groups in the capsule around splenic tissue, organized structure, fibrosis and revascularization (P>0.05).The hemosiderinpigmentation was significantly higher in Au-12 group (P=0.03).Conclusions: The results of this study showed that autotransplanting about 15 percent of splenic tissuewere associated with a high success rate in tissue structure rearrangement.Therefore, spleen autotransplantation even in small sizes was highly recommended in cases of unavoidable splenectomy

A Case Report: Total Parathyroidectomy with Autotransplantation for Secondary Hyperparathyroidism

Secondary hyperparathyroidism (HPT) usually result from parathyroid gland hyperplasia that produces excess parathyroid hormone (PTH). Decreased renal function leads to elevate serum phosphate levels and reduce vitamin D production, which results in hypocalcemia. Skeletal resistance to PTH results in persistently and frequently extremely elevated PTH levels and renal osteopathy. Treatment of choice for secondary HPT is medical management including calcitriol and vitamin D. However, for some cases in calciphylaxis and the failure including PTH >800 pg/mL or osteoporosis under maximal medical management surgical intervention could be an alternative option. We described a case of 47-year-old woman with surgical intervention for secondary hyperparathyroidism.

Value of three-dimensional visualization technology in preoperative evaluation of liver autotransplantation for end-stage hepatic alveolar echinococcosis / 中国血吸虫病防治杂志

Objective To evaluate the value of the three-dimensional visualization technology for the preoperative assessment of liver autotransplantation for end-stage hepatic alveolar echinococcosis. Methods A total of 8 patients with end-stage hepatic alveolar echinococcosis undergoing liver autotransplantation in Qinghai Provincial People’s Hospital from May 2013 to July 2017 were collected. All cases received preoperative abdominal CT scanning and dynamic three-phase enhanced CT scanning, and the original CT data were transferred to the human 3D visualization virtual surgical planning system. The volumes of Echinococcus multilocularis and pre-resected liver were measured using the 3D visualization reconstruction, and the relationship between the lesion and the neighboring tissues was observed. The value of the 3D visualization technology for the preoperative assessment of liver autotransplantation for end-stage hepatic alveolar echinococcosis was assessed by comparing with the intraoperative findings. Results The 3D visualization reconstruction model clearly displayed the adjacent relationship between the lesions of end-stage hepatic alveolar echinococcosis and the neighboring tissues, and no significant difference was seen between the pre-resected liver volume in 3D visualization reconstruction model and the actually resected liver volume (t = 1.083, P > 0.05). Conclusions 3D visualization technology is feasible to develop a reasonable scheme for liver resection and vascular anastomosis for end-stage hepatic alveolar echinococcosis prior to liver autotransplantation, which may increase the success of surgery and improve the prognosis.

The application of robotic nephrectomy, work bench surgery with robotic kidney autotransplantation in nephron-sparing surgery of complex renal tumors / 中华泌尿外科杂志

Objective To investigate the safety and feasibility of robotic nephrectomy,work bench surgery with robotic kidney autotransplantation in the treatment of complex renal tumors.Methods The clinical data of 5 patients with renal tumors admitted from January 2018 to July 2018 were analyzed retrospectively.There were 4 males and 1 females.The median age was 49 years old,ranging 32-66 years.The median body mass index was 25.6 kg/m2,ranging 21.1-27.8 kg/m2.Serum creatinine level was 87.2 μmol/L,ranging 78.0-88.9μmol/L before bench surgery.5 patients had multiple bilateral renal tumors and had undergone laparoscopic or robotic partial nephrectomy on the contralateral kidney.For bench surgery kidney,4 cases were on the left side and 1 case was on the right side.Each kidney has more than 2 separate tumors,combined with complete endophytic tumors,tumors larger than 7 cm in diameter or hilar tumors.5 patients were all performed robotic nephrectomy,work bench partial nephrectomy with robotic kidney autotransplantation under general anesthesia.The patient was first in a lateral decubitus position for robotic nephrectomy,and the kidney was removed through a median 6 cm periumbilical incision.After kidney removal,kidney tumors were resected and kidney was reconstructed on a hypothermic working table.Then the kidney was packed in a plastic bag,filling with ice slush.The corresponding parts of the plastic bag were cut to expose the renal artery and vein.Finally,the patient was moved to lithotomy position with Trendelenburg tilt of 20°,and the autologous kidney wrapped in the plastic bag was placed through the previous periumbilical incision into the abdominal cavity for robotic kidney autotransplantation.The renal artery and vein were anastomosed end-to-side with the right external iliac artery and vein.The ureter and bladder were anastomosed.Autologous kidneys were placed in abdominal cavity in 4 cases,and placed in right iliac fossa with retroperitonealization in 1 case.Ice slush on the surface of the autologous kidney did not completely melt before the blood supply was restored during the operation,and the autologous kidney immediately urinated after the blood supply was restored.Results All surgeries were performed successfully without conversion to open surgeries.The total operation time was 460 min,ranging (415-645 min),the time of robotic nephrectomy was 120 min,ranging (74-300 min),the time of robotic kidney autotransphntation was 135 min,ranging(103-163 min),the warm ischemia time was 3 min,ranging (1.5-6.0 min),the cold ischemia time was 182 min,ranging(135-210 min),the rewarming time was 50 min,ranging(45-55 min),the estimated blood loss during operation was 100 ml,ranging(50-300 ml),and the hospital stay was 6 d,ranging(5-9 d).The number of resected tumors was 4,ranging(2-6).The pathology reveals clear cell carcinoma in 3 cases and chromophobe cell carcinoma in 2 cases.The surgical margins were all negative.The serum creatinine levels were 111.1 μmol/L (87-217.6 μ mol/L) and 106.1 μmol/L (87.1-172 μmol/L) on the 7th and 30th day after operation,respectively.One month after operation,CT showed that the function and morphology of the autologous kidneys were fine.No recurrence or metastasis was found in 5 patients during a median follow-up of 7 months,ranging (5.4-11.7 mon).Conclusions For patients with complex renal tumors who cannot undergo in situ partial nephrectomy,robotic nephrectomy,work bench surgery with robotic kidney autotransplantation can completely remove the tumors,maximize the preservation of renal function and minimize the trauma of patients,making the ultimate means of nephron-sparing surgery for patients with complex renal tumors more minimally invasive and safe.

Application of autologous cartilage and prevention of its complications in rhinoplasty / 中华整形外科杂志

Because of the versatility of autologous cartilage and proven advantages, it has been widely used in all kinds of rhinoplasty. Autologous cartilage have good biocompatibility with less complications such as infection, extrusion of graft, compared to biological synthetic materials, so it is generally considered the primary graft for nasal surgery especially septal, conchal and costal cartilage. With the popular clinical application of autologous cartilage, problem also arised and considered.The purpose of this paper is to review the application of autologous cartilage and complications in rhinoplasty.

Primary rhinoplasty for female patients utilizing autologous costal cartilage transplantation / 中华整形外科杂志

Objective@#The purpose is to investigate the validity of a surgical technique that utilizes autologous costal cartilage grafts in primary rhinoplasty for female patients.@*Methods@#From July 2015 to July 2017, 137 cases received primary rhinoplasty with various types of grafts originated from autologous costal cartilage to correct the unpleasant nasal appearances including low dorsum, poorly defined nasal tip and wide alar base.@*Results@#With 6 to 36 months follow-up, six patients(4.3%) exhibited noticeable changes in nasal contour due to graft warping. Revision surgeries were commenced to correct those minor deformities, resulting in satisfactory outcome.All other cases presented significant improvements of the nasal appearance.@*Conclusions@#Autologous costal cartilage is a good source for primary rhinoplasty cases.

519 cases of autogenous costal cartilage combined with polytetrafluoroethylene rhinoplasty / 中华整形外科杂志

Objective@#The purpose of this study is to explore the method and effect of autogenous costal cartilage combined with polytetrafluoroethylene in comprehensive rhinoplasty.@*Methods@#Among the 519 included cases, 441 cases underwent primary rhinoplasty, and 78 cases underwent revision after initial rhinoplasty. The 6th or 7th costal cartilage, with 4-5 cm in thickness, was taken to make a columella supporting graft, a nasal septum extension graft, a lateral foot support graft, and a nose tip shield graft. The nasal shape is corrected by the reconstruction of nasal tip supporting structure. Polytetrafluoroethylene was used as a nasal dorsal graft.@*Results@#After 3-24 months of follow-up, 510 patients received satisfactory nasal tip and nasal dorsum esthetics. One patient had a prosthesis removement one year after surgery. Eight cases showed a decrease in nasal tip excursion 2-6 months postoperatively, with reduced nasal tip prominence. However, satisfactory results obtained, after further correction 6 months later.@*Conclusions@#The combination of autogenous costal cartilage and polytetrafluoroethylene for rhinoplasty is an appropriate surgical procedure for Chinese.

Individualized rhinoplasty with costal cartilage assisted by digital simulation and three-dimensional printing technology / 中华整形外科杂志

Objective@#This study is to manufacture the templates for costal cartilage carving, by digital simulation and three-dimensional printing technology, to realize the individualization of rhinoplasty.@*Methods@#Preoperative simulated images and 6-month postoperative images, of 10 patients were included in this study. The simulation was produced using Geomagic Studio 2013 and 3-matic Research 9.0 software, according to patients′requirements. The templates for costal cartilage carving during the operation, were designed, measured and three-dimensional printed. Statistical analyses were performed using paired t-test.@*Results@#The dorsal length in preoperative simulation was significantly shortened, compared with postoperative [(4.73±0.11) cm vs. (4.88±0.16) cm, t=-0.465, P=0.001). The nasal tip projection in preoperative simulation is parallel with postoperative[(2.66±0.10) cm vs. (2.66±0.11) cm, t=0.068, P=0.947). The nasolabial angle in preoperative simulation is slightly greater than postoperative, yet failed to reach statistical significance (95.3±3.1 degrees vs. 94.3±3.0 degrees, t=1.936, P=0.085). Most of the patients were satisfied with both the preoperative simulation and the surgical outcomes.@*Conclusions@#With the assistance of digital simulation and three-dimensional printing technology, the expectation of rhinoplasty patients can be visualized, which is helpful to minimize the difference between surgical outcomes and the patient′s anticipation. Therefore, the digital simulation and three-dimensional printing technology should be considered, to provide individually surgical plan for this group of patients.